Cri du chat (cry of the cat): Deletion of a small portion of 5 th chromosome. Children with this disease have a small head with unusual facial features, severe mental retardation and make a sound like a cat while crying. 2) Duplication: The presence of part of a chromosome in excess is known as duplication. If the duplication is present only in

Cri du Chat Syndrome (CdCS) is a genetic disease resulting from a deletion of the short arm of chromosome 5 (5p-). Its clinical and cytogenetic aspects were first described by Lejeune et al. in 1963 . The most important clinical features are a high-pitched cat-like cry (hence the name of the syndrome), distinct facial dysmorphism, microcephaly

Keywords: 5p deletion, Cri‐du‐chat syndrome, prenatal diagnosis, single nucleotide polymorphism array. This study provides clinical and molecular characterization for 12 prenatal case of Cri‐du‐chat syndrome (CdCS) and genotyping‐phenotyping analysis for these cases. The findings from the present study are important for genetic
The most obvious physical sign of Cri du Chat syndrome is a cat-like cry in babies and young children. This is caused by problems in the child's larynx and nervous system. A third of children lose the cry by the time they're 2 years old. Other common physical signs and symptoms might include:

Cat cry at birth, small head, wide eyes signal disabling "cri du chat" syndrome. By ABC News. October 12, 2008, 12:23 PM. Oct. 13, 2008 -- In 1988, Katie Castillo was born with the cord around her

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symptoms of cri du chat